Organocatalytic asymmetric strategies to carbocyclic structures by γ-alkylation-annulation sequences.
نویسندگان
چکیده
Attractive carbocyclic structures are accessed via a highly regio- and enantioselective aminocatalytic γ-addition of cyclic enals to vinyl phosphonates followed by a one-pot intramolecular Horner-Wadsworth-Emmons reaction. It is also demonstrated that nitro olefins can act as electrophiles in a similar reaction concept, providing carbocycles in equally high stereoselectivity.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 89 شماره
صفحات -
تاریخ انتشار 2014